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Cosmetics

Preventative Healthcare

Relfydess® London

Relfydess® - The next generation of anti-wrinkle injections has arrived

Works Faster. Lasts Longer.

Fine lines between the brows. Crow’s feet that deepen every time you smile. The kind of expression lines that make you look more tired, or more frustrated, than you actually feel. At Neu Clinic, we treat them with Relfydess — a new generation botulinum toxin type A treatment, developed by Galderma, designed to soften these lines quickly, smoothly and with results that last.

Treatment at a Glance

90-120 Minutes

Treatment Time

2-4 Years

Duration

Instant

Results

Local Anaesthetic

Anaesthetic

Relfydess®

Pay in 3 interest free monthly instalments

Call 03301331835

Whatsapp +447507680820

£100 OFF New Clients

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What Is Relfydess?

Relfydess (relabotulinumtoxinA) is a purified botulinum toxin type A injectable, licensed for the treatment of moderate to severe glabellar lines (the vertical lines between the eyebrows) and lateral canthal lines (crow’s feet) in adults under 65. Like other botulinum toxin treatments, it works by temporarily relaxing the small facial muscles responsible for these expression lines, smoothing the skin above them for a more refreshed, rested appearance.

What sets Relfydess apart is its next-generation formulation, engineered for a notably fast onset and long-lasting results — bringing together two qualities that have traditionally been a trade-off in anti-wrinkle treatments.

Why Patients Are Choosing Relfydess

Visibly faster results. In clinical data, a meaningful proportion of patients began seeing improvement within the first day or two of treatment — a much faster onset than patients typically experience with standard botulinum toxin products, where results usually build gradually over three to fourteen days.

Results that go the distance. Clinical follow-up has shown a high proportion of patients still experiencing visible improvement at the six-month mark, offering excellent longevity between top-up treatments.

A refined, natural look. Precisely dosed and administered, Relfydess is designed to soften expression lines while preserving natural movement and expression — never leaving you looking “frozen.”

A trusted formulation. Relfydess is developed and manufactured by Galderma, a company with a long-standing reputation in medical aesthetics, and is licensed for use in the treatment areas offered at Neu Clinic.

A good option if other toxins haven’t worked as well for you. Some patients who feel their results from other botulinum toxin brands wear off unevenly or too quickly find Relfydess a welcome alternative worth discussing at consultation.

What to Expect: Your Treatment Journey

1. Consultation & Assessment We start with a thorough consultation to understand your concerns, assess your facial muscle movement, and confirm that Relfydess is a suitable and safe option for you. We’ll talk openly about what results you can expect and answer any questions before you decide to proceed.

2. The Treatment Using a fine needle, a precisely calculated dose is injected into the targeted facial muscles — typically five injection points for glabellar lines, six for crow’s feet, or a combination of both. The treatment itself usually takes no more than 10–15 minutes, with no need for anaesthetic, though numbing cream can be applied first if you’d prefer.

3. Aftercare You can return to most normal activities straight away. We’ll give you simple aftercare guidance — including avoiding strenuous exercise, lying flat, or touching the treated area for a few hours — to help your results settle as intended.

4. Follow-Up We’ll check in with you around two weeks after treatment to assess your results and, if needed, make any small refinements.

Results & Longevity

Many patients begin to notice initial changes within the first few days, with full results developing over the following one to two weeks as the treatment takes full effect. Clinical data supports results lasting up to around six months for many patients, though this varies by individual, treatment area and muscle strength. We recommend a minimum interval of 12 weeks between treatments, and we’ll help you plan a maintenance schedule that keeps your results looking consistently natural.

Is Relfydess Right for You?

Relfydess may be a good option if:

  • You have visible glabellar lines and/or crow’s feet that bother you
  • You’re aged under 65 and in good general health
  • You want a treatment with a fast-acting profile and strong longevity
  • You’ve tried other anti-wrinkle treatments and are looking for an alternative

It isn’t suitable for everyone. Relfydess should not be used if you are pregnant or breastfeeding, have a known neuromuscular disorder (such as myasthenia gravis), or have an infection at the proposed injection site. We’ll review your full medical history at consultation to confirm suitability.

As with all botulinum toxin treatments, side effects can include injection site reactions, headache, and temporary bruising or swelling; rarely, effects of the toxin can spread beyond the treatment area, causing symptoms such as drooping eyelids or visual disturbance. We’ll talk you through the full safety profile during your consultation, so you can make a fully informed decision.

Interested in this Treatment ?

Speak to one of our team or book a FREE Consultation today!

Call Us

03301331835

Whatsapp Us

+447507680820

Your Questions Answered

If you can’t find the answers to your questions, get in touch with the clinic and we will get back to you as soon as we can.

Is Relfydess the same as Botox?

Relfydess and Botox are both purified botulinum toxin type A products used to treat expression lines, but they’re different formulations from different manufacturers. Relfydess is a newer-generation product designed with a notably fast onset and strong duration of results. Your practitioner can help you decide which is the better fit for your goals.

Some patients notice early changes within the first day or two, with the full effect typically visible within one to two weeks, as the treatment takes hold.

Clinical data shows many patients maintaining visible improvement at six months post-treatment, though individual results vary depending on muscle strength, metabolism and treatment area.

Discomfort is generally mild and brief — most patients describe it as a quick pinch or scratch at each injection point. Numbing cream is available if you’d prefer extra comfort.

Relfydess is a licensed botulinum toxin injectable, administered by our trained practitioners following a full medical assessment. As with any injectable treatment, it carries risks and potential side effects, which we’ll discuss in detail during your consultation so you can decide whether it’s right for you.

No — when dosed correctly, Relfydess is designed to soften expression lines while preserving natural facial movement, so you look refreshed rather than expressionless.

Medically Reviewed by 

Founder | Cosmetic Doctor

GMC Number: 7561320

Review Date

Next Review

Published On 

Last Update 

Dr David Stark

MD MRCS Surgeon | Endolift® Specialist | GMC: 7611200

Dr Stark is a highly experienced Plastic Surgery Registrar with over seven years of NHS and aesthetics experience specialising in advanced Endolift® procedures. He has been awarded recognition of excellence from Endolift and a recognised leading Endolift practitioner. By combining his surgical expertise with cutting-edge laser technology, he delivers comprehensive, non-surgical facial rejuvenation that yields exceptional results.

Alongside his surgical background, Dr Stark has extensive experience in non-surgical injectables. He applies a deep understanding of facial anatomy, ageing, and tissue behaviour to deliver refined, natural-looking results, with a strong emphasis on safety, balance, and subtle enhancement.

Academically driven, Dr Stark has authored multiple peer-reviewed publications and book chapters. His research has been published in the Journal of Plastic, Reconstructive & Aesthetic Surgery, and he has received national recognition, including First Prize for Best Oral Presentation at the Southwest Oncoplastic Breast Surgery Meeting. He is a regular contributor to national and international conferences and has published chapters in leading surgical texts, including 50 Landmark Papers That Have Shaped Modern Breast Surgery.

Passionate about medical education, Dr Stark has founded and led several teaching programmes across England, including an innovative on-call simulation programme for final-year medical students.

In aesthetic practice, Dr Stark combines surgical precision with an artistic eye to provide personalised, evidence-based injectable treatments, tailored to each client’s individual anatomy, goals, and long-term aesthetic wellbeing.

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Dr Tony Kaliya

MBChB Founder & Medical Director | GMC: 7561320

Dr. Tony Kaliya is an award-winning specialist in cosmetic medicine renowned for delivering natural, transformative results with cutting-edge aesthetic techniques. With an exceptional eye for detail and a meticulous approach to facial artistry, he has become a leading name in advanced cosmetic procedures having performed thousands of procedures to date.

His work and expert insights have been featured in a number of high-profile publications, including Vogue, Hello! Magazine, and Marie Claire, further cementing his reputation as a trusted authority in the cosmetic medicine industry.

Dr. Kaliya has worked across several prestigious central London clinics, including Harley Street, where he specializes in transformative full facial rejuvenation procuderes and advanced Endolift® procedures using advanced, highly technical techniques. He is dedicated to achieving subtle yet impactful facial transformations, restoring youthfulness while preserving individuality. HIs philosophy is centered on precision treatments that enhance natural beauty, ensuring that each client achieves an incredibly natural rejuvenated look.

Dr. Kaliya also has a passion for preventative healthcare and is the founder of Neuwell—a preventative healthcare company utilizing the world’s most advanced diagnostic technologies. Neuwell enables people to detect diseases years in advance, before symptoms develop, with a mission to help people live longer, healthier, and happier lives. 

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Situated Behind Selfridges,

NEU Clinic Marylebone, London

Location

UNTIL 
1 Orchard St 
London 
W1H 6HJ

Call Us

03301331835

Whatsapp Us

+447507680820

Opening Hours

Monday - Friday - 10am - 9pm
Saturday - 10am - 4pm
Sunday - Closed

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Step 1

Book a FREE Consultation

We require new patients to attend a consultation so we can better understand what it is you are MOST concerned about. Need flexibility? Sure, we can move your appointment around if you let us know within 72 hours of your booking. We do require a card on file in the event you do not show up to your appointment and fail to move or cancel the appointment.

Step 2

Come on Over

It’s time to come in and meet us for your consultation! We’ve created a safe, comfortable and relaxed space so you can feel at home. This is your opportunity to get to know Dr Tony, and share your aspirations. We ask that during this stage you keep an open mind, because you may have a vision but Dr Tony could advise differently based on their assessment of you.

Step 3

Start Your Plan

You’ve had your consultation, you’re excited, and we’re all happy with your treatment plan – now it’s time to make the magic happen. This can either be started in the same session as your consultation or at a more convenient date. With each visit, you’ll notice your self-esteem rising as we enhance your natural beauty, bringing symmetry and harmony to your appearance.